PhD & Postdoc positions in mechanisms of tumor dormancy 100%
Date de publication :
30 mars 2025Taux d'activité :
100%- Lieu de travail :Basel
Résumé de l'emploi
Postes de doctorat et postdoctorat à l'Université de Bâle. Une opportunité unique dans un environnement de recherche dynamique.
Tâches
- Étudier les mécanismes cellulaires de la dormance tumorale.
- Utiliser des modèles murins et des échantillons de patients.
- Appliquer des techniques OMICs avancées et d'imagerie.
Compétences
- Expérience en recherche sur les métastases ou l'immunologie requise.
- Compétences en biologie moléculaire et cellulaire essentielles.
- Capacité d'analyse et de pensée critique fortement souhaitée.
Est-ce utile ?
PhD & Postdoc positions in mechanisms of tumor dormancy 100%
Published 21 March 2025 Workplace Basel, North West Switzerland, Switzerland CategoryInnovation
Start in June 2025
The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need.
With more than 70 research groups and 800 employees, the Department of Biomedicine is the largest department at the University. We are located in the heart of Basel at 6 different locations. Be part of our future!
Positions are available in the laboratory of Professor Momo Bentires-Alj at the Department of Biomedicine (DBM). The successful candidate will work on the molecular and cellular mechanisms of breast tumor dormancy with a focus on the tumor microenvironment.
Selected publications of our lab include: 1- Glucocorticoids promote breast cancer metastasis. Obradovic MMS et al., Nature 2019. 2- Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy. Correia AL et al., Nature 2021. 3- Feed-forward loops between metastatic cancer cells and their microenvironment-the stage of escalation. Baumann Z, et al., EMBO Mol Med. 2022. 4- Optimized full-spectrum flow cytometry panel for deep immunophenotyping of murine lungs.
Baumann Z et al., Cell Rep Methods. 2024. 5- Microenvironmental Regulation of Dormancy in Breast Cancer Metastasis: "An Ally that Changes Allegiances". Kabak EC et al., Adv Exp Med Biol. 2025.
Your position
The successful candidate will work on molecular and cellular mechanisms underlying the reciprocal crosstalk between cancer cells and the metastatic microenvironment using mouse models and patient samples. The candidate will implement a variety of OMICs at single cell and spatial levels, as well as standard and advanced molecular and cellular biology approaches.
Your profile
A strong experience in metastasis research and/or the tumor microenvironment (e.g., immunology). Expertise in mouse models, single cell OMICs and/or advanced imaging techniques (e.g., intravital imaging) is a plus. The candidate should demonstrate ability to think critically and a strong aptitude for interpreting/ analyzing complex data. We are looking for someone with excellent organizational skills, creative, highly motivated, and fluent in English with strong written and oral communication skills.
We offer you
A stimulating, challenging and interdisciplinary translational research environment, state-of-the-art technologies and core facilities, and attractive employment conditions. The DBM is an international institute pursuing basic, translational and clinical research, with access to cutting-edge core facilities and in the heart of multicultural city of Basel.
Lab website: https://bentireslab.org/')
Application / Contact
Please upload your CV, a summary of your research experience and interests, techniques that you are competent in, and the contact details of three referees including your current PI at:
PhD position: https://biped.dbm.unibas.ch/apply/phd-position-in-mechanisms-of-tumor-dormancy-start-in-june-2025')
Postdoc position: https://biped.dbm.unibas.ch/apply/postdoc-position-in-mechanisms-of-tumor-dormancy-start-in-june-2025')
Application deadline: Applications will be reviewed as they arrive.
Contact: thmrjobapplication- E-Mail schreiben
www.unibas.ch')