Biomarker Computational Scientist

Conditions of Employment for US position

• Eligible to work in U.S. (U.S. citizenship, or work permit/authorization)

Why us

• Be part of a team pioneering cutting-edge research at the forefront of precision medicine
• Brand new working space. Friendly office/lab environment!
• Great benefits package

If you think you are a strong fit for this position, please apply today!!

To Apply: Please send your CV and Cover Letter to E-Mail schreiben. Please specify the position you are applying for and use the "Biomarker-COMP" identifier in your cover letter and email subject line.

About the job

HAYA leverages AI/ML models to decipher the regulatory genome, identify disease modifying targets in the non-coding genome, develop effective drugs, and identify circulating biomarkers. We are seeking highly motivated candidates with experience on biomarker discovery and validation for chronic diseases, to reinforce the biomarker team. As an experienced and engaged Biomarker Computational Scientist, you will work in close collaboration with discovery, pre-clinical and clinical R&D teams. You will apply your scientific acumen and creativity to build ViewHAYATM, a top-notch platform for biomarker discovery and validation. You will drive this platform forward to identify and develop biomarker panels (including PD and CDx panels) for HAYA’s therapeutic assets.

Primary Responsibilities:

• Drive the computational analyses to discover novel biomarkers, including pharmacodynamics and predictive biomarkers. We focus on different classes of molecules (e.g. lncRNAs, proteins) and profiling techniques.
• Design, conceptualize and develop computational procedures, and support the design of experimental and analytical procedures, based on genomics-based biomarker assays (e.g. proteomics, transcriptomics).
• Be a subject expert on evaluating computational challenges and opportunities related to the identification of biomarkers using large scale genomics technologies and assays.
• Interpret computational findings in the context of disease biology and clinical implications.
• Actively participate in internal and external scientific projects and meetings through presentations and critical evaluation of both internal results and emerging scientific literature.

Qualifications:

• PhD or equivalent experience in Biology, Computational Biology or related field.
• Strong experience in the analysis of data for biomarker discovery and validation. The ideal candidate has an extensive understanding of different molecular profiling techniques.
• Strong expertise in genomics biomarker assays development.
• Strong knowledge with tools, and resources used for the analysis and interpretation of omics data.
• Proficiency with statistical analysis in Python or R.
• English proficiency, strong verbal and written communication skills.
• Experience with software development platforms (e.g. Gitlab) and software development procedures and best practices is a strong plus.

HAYA Therapeutics is a precision RNA-based therapeutics company that discovers and develops innovative genomic medicines for the treatment of fibrosis and other serious health conditions associated with aging. The company’s discovery engine focuses on long non-coding RNAs (lncRNAs) within the “dark matter” of the human genome -- key tissue and cell-specific drivers of multiple disease processes including fibrosis -- to identify novel targets and drug candidates with the potential for greater efficacy and safety than existing treatments.

Headquartered in Lausanne, Switzerland with laboratory facilities in San Diego, USA, HAYA is a rapidly growing company led by a world-class team and supported by a strong investor consortium.