Genetics und Genomics Lab research associate (m/f/d)

We are looking for a motivated and committed Genetics & Genomics Lab research associate for our client, F. Hoffmann-La Roche Ltd. based in Basel, for a 24 month assignment with option for extension.

As an engaged Genetics & Genomics Lab Research Associate, you will play a key role in the development and implementation of genomic assays for biomarker analysis in both pre-clinical and clinical settings. Your primary responsibility will be hands-on laboratory work, driving innovation and advancing our understanding of genetic and genomic mechanisms in support of therapeutic development.

Tasks

• Develop, validate, and implement genetics and genomics-based biomarker assays (e.g., epigenetics, SNVs, CNVs, gene expression signatures, circulating DNA/RNA) to support pre-clinical studies and early-phase clinical trials, characterizing pharmacodynamics and mechanisms of action for novel therapeutics.
• Evaluate and apply cutting-edge genetics and genomics technologies (e.g., single-cell sequencing, spatial-omics, ddPCR) to maximize insights from limited and valuable pre-clinical and clinical samples following Roche GCP standards
• Deliver high-quality biomarker data to project biology and biomarker teams, ensuring impactful contributions to therapeutic development.
• Ensure compliance with Safety, Health, and Environment (SHE) regulations in all laboratory and operational activities, contributing to a safe and sustainable research environment.
• Inspire and train other scientists and associates in applying novel technologies and facilitate the transfer of innovative methods to external collaboration partners.

Must Haves

• Master's degree or higher in molecular biology, biochemistry, or a related field with substantial experience in biomarker assay development in pre-clinical or clinical settings.
• Deep hands-on expertise in molecular biology techniques (e.g., qPCR, ddPCR) and next-generation sequencing (NGS) platforms, including single-cell and spatial-omics technologies.
• Proficiency in developing, validating, and applying genomic assays across multiple platforms and sample types (e.g., tissue, liquid biopsies).
• Familiarity with implementing genetics and genomics assays in compliance with Good Clinical Practices (GCP) is a plus.
• Fluency in English is required, German would be nice to have
• Ability to think creatively and rigorously in evaluating and developing new technologies for current and emerging scientific modalities.
• Strong focus on ensuring operational compliance in the storage e.g. tracking, and management of samples and data, adhering to established regulatory and organizational standards.
• Strong team player with a collaborative spirit, able to work independently and within agile, matrixed teams.

Nice to Haves

• Previous Pharma experience

Are you interested? Don't hesitate and send us your complete application documents online today.
 

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Kontakt
Alessandro Forcina

Arbeitsort
Basel

Pensum
100%

Position
Mitarbeiter

Branche
Pharma + Chemie + Life Science